This company uses AAV-based viral vectors to deliver a gene. These vectors will be injected into the subthalamic nucleus in the brain, introducing their genes into brain cells and causing the expression of a protein (glutamic acid decarboxylase or GAD) that can increase the production of GABA.
GABA is a neurotransmitter that brain cells spray between them to inhibit each other. This way, the overactivation (e.g. tremor) in Parkinson’s patients could be mitigated.
This approach does not address the causes of Parkinson’s disease, it mainly focuses on reducing some symptoms.
