ALL COMPANIES

This company develops small molecules to upregulate autophagy to treat Parkinson’s disease.  Autophagy is the process which cells use to...

This company uses AI and tissue banks to find novel mechanisms and pathways involved in neurodegenerative diseases, including Parkinson’s disease.

This company is developing methods to activate the lysosomes, or improve lysosomal function, in order to treat Parkinson’s disease. One...

Doxycycline is a small molecule (originally an antibiotic) that is being investigated as a possible alpha-synuclein (aSyn) inhibitor. Alpha-synuclein aggregation...

1st-102 (FB-101)  is a small molecule that functions as a c-Abl kinase inhibitor. c-Abl is a kinase implicated in neurodegenerative...

ikT-148009 is another small molecule that acts as a c-Abl kinase inhibitor. Inhibiting the c-Abl pathway is thought to protect...

This is a small molecule that functions as a LRRK2 kinase inhibitor. Like NEU-411 and NEU-723, it inhibits the kinase...

GT-02287 is a small molecule that acts as a GCase enhancer. GCase (glucocerebrosidase) is an enzyme involved in breaking down...

Ambroxol is a small molecule functioning as a GCase enhancer, aimed at increasing the activity of glucocerebrosidase to reduce the...