ALL COMPANIES
Athira Pharma
Fosgonimeton (ATH-1017) is a small molecule that acts as a HGF (hepatocyte growth factor) agonist. HGF is involved in cellular...
Technical University of Munich
Fasudil is a small molecule that functions as a ROCK (Rho kinase) inhibitor. ROCK inhibition is thought to reduce neuroinflammation...
Cannabis-derived substances
Various companies are developing drugs based substances found in cannabis, such as cannabidiol. Parkinson’s UK & King’s College London: researches...
Kyowa Kirin
Istradefylline (KW-6002) is a small molecule acting as an adenosine receptor antagonist. It targets cognition and dementia by blocking adenosine...
Celon Pharma
CPL-36 is a small molecule that inhibits phosphodiesterase 10A. It is being studied for its effects on dyskinesia, which are...
University of Queensland
Levetiracetam is a small molecule that functions as an SV2A modulator, targeting synaptic vesicle proteins involved in neurotransmitter release. This...
Jazz Pharma
JZP-385 is a small molecule that acts as a T-type calcium channel antagonist. This therapy aims to address motor impairment...
Intra-Cellular Therapies
Lenrispodun (ITI-214) is a small molecule that inhibits phosphodiesterase 1. This mechanism is aimed at improving motor impairment by enhancing...